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People on the Internet have surmised that each Nutri-meds pill is roughly equivalent to a fourth grain of the prescription desiccated thyroids. This is not very much, but it is enough to help an adult. One Nutri-meds pill per day is good general nutritional support. If we were still eating blood pudding and other such traditional foods, then we would be getting about a fourth grain in our daily diet. Most healthy people will Thyroid 21 have no problem with this much. However, if you are particularly weak, you need to be more cautious. If you decide to purchase these undenatured thyroid glandulars, then you must take on the responsibility of this choice. Do not abuse them, or the FDA will take away everyone’s right to use them. Especially if this is the first time you have taken such a product, you need some guidance. Look for a progressive MD or seek the advice of a naturopath. You should request that your doctor take periodic blood thyroid tests. Or order your own blood thyroid tests. (See the section on ordering hormone tests in the progesterone/estrogen chapter.) Also, read and understand the precautions section in this chapter. Thyroid glandulars that have not been denatured can be purchased at www.nutrimeds. com/thyroid.htm, phone (888)-265-3353. Both the porcine (pig) and bovine (cattle) glandulars are available. Although people usually react better to the porcine, once in a while, a person will do better on the bovine. The Blood Tests For Thyroid Polly: Many doctors, especially those bound by HMO (Health Maintenance Organization) rules, rely only on the TSH (thyroid stimulating hormone) blood test to screen for thyroid problems. However, this can miss some cases of hypothyroidism. For instance, excess serotonin influence in the brain of people with autism or fibromyalgia could suppress TRH (Thyrotropin Releasing Hormone), which tells the brain to create TSH. Both the autistic and those with fibromyalgia will very often have a lowered TSH response to TRH. [3] These thyroid problems will be missed with just a TSH test. Recently, the conventional dogma has come closer to the position of the alternative doctors. Mary Shoman’s newsletter contains an article entitled “Major Reversal at American Association of Clinical Endocrinologists Regarding TSH and Diagnosing Hypothyroidism.” The essence of the article is that The American Association of Clinical Endocrinologists (AACE) was previously adamant that patients not be treated if their TSH reading were within “normal” limits. Now they state in their material provided for the January 2001 Thyroid Awareness Month that: “Even though a TSH level between 3.0 and 5.0 uU/ml is in the normal range, it should be considered suspect since it may signal a case of evolving thyroid underactivity.” (AACE Press Statement, January 18, 2001) This new lower acceptable TSH range for treating patients is one step in the right direction. At least, if your doctor has heard about it, then it may help. In contrast, many of the alternative doctors had already been using a TSH of 2.0 or higher as the range of readings where they suspect a thyroid problem. Most of the TSH readings from healthy people are around 1.0. Here is a graph of the population’s TSH readings: www.thyroid.org.au/Information/NormalTSH.ht ml Rue: Just wanted to add that candida can cause a thyroiditis that will not raise the TSH above normal limits or just a bit above. However, the person may have symptoms of someone with a TSH of 60. Polly: Yes. If you only test TSH, then you could miss that condition. There are many different tests for thyroid function, and not one of them will catch all the cases of low thyroid. However, some doctors say that all those problems are now solved because they have the latest and greatest tests—free T4 and free T3. Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 22 The hope is that the “free” or unbound thyroid levels will show what the cells actually have available to them for use. Yet, this isn’t completely true. These tests ignore the protein bound thyroid, which is 95% of the thyroid found in the blood. The brain is an example where the protein-bound hormone is the active form, not the free thyroid hormone. But the test for free thyroid is important. If free thyroid is low, yet the bound thyroid looks normal, then this is an indication that the body might be suffering from too much estrogen. When the symptoms of hypothyroidism are present, and yet all the aforementioned blood tests don’t show a problem, then a few doctors will resort to the more expensive Thyrotropin Releasing Hormone (TRH) blood test. This test will show if the brain is having trouble producing enough TSH. The TSH response can be suppressed by stress, lack of sleep, or exposure to lipopolysaccarides from gram-negative intestinal bacteria. [4] About half the people with fibromyalgia will fail this test. About a third of those with autism will fail this test. [5] Many of those with depression will fail this test, especially if it is given in the evening. [6] However, don’t be in a hurry to get the TRH test. With this test, you are given an injection of TRH to stimulate the pituitary into producing TSH. There is a chance that the TRH will overstimulate a weak pituitary and harm it. There would be less risk and certainly less expense if more doctors were willing to give a trial of thyroid based on symptoms. Every doctor should know that the standard blood tests couldn’t possibly cover all the possibilities. Yet many doctors won’t treat unless they have found a blood test that indicates a problem. Even if the blood test shows a problem, they are very reluctant to treat if it is a child. Doctors are acutely aware of peer pressure, their employer’s guidelines, and/or the opinion of their local medical board; they feel their hands are tied. These policies may save the doctors from getting sued, but it isn’t helping the patient. It would be almost impossible to prove that a lack of thyroid hormone treatment was the reason a patient later developed pneumonia, heart disease or cancer. Yet it would be fairly easy to drag a doctor into court claiming that unnecessary treatment harmed someone. Unfortunately, our litigious society creates a situation where it is safer for doctors not to help their patients. Why Isn’t The Blood Thyroid Level A Reliable Indicator? Polly: Many of us seem to require more thyroid hormone than the blood tests indicate. Some think it is due to the yeast or bacteria toxins that are in the gut. Others, point to the interference caused by high antibody levels that can be associated with yeast overgrowth. The blood tests can be dangerously misleading. An example was a man admitted to a French hospital with severe hypothyroidism. He was so bad off that he was exhibiting fullblown myxedema (puffy skin that doesn’t indent when pressed due to accumulation of mucopolysaccharides). Still his blood thyroid tests were normal. (One of the Barnes Tapes by Dr. Hertoghe mentions this incident.). According to a 1994 lecture by Jacques Hertoghe, MD, the blood tests are a poor indicator of the less severe forms of hypothyroidism because there is a slow clearance from the blood of the thyroid hormones when there is hypothyroidism. The thyroid hormones aren’t being used very quickly, so more remains in the blood. This makes it look like there is enough thyroid hormones in the blood even though the patient is hypothyroid. Dr. Hertoghe listed these reasons for the slow clearance: Thyroid 23 1) a reduced blood volume, with overall arterial vasal constriction (including in the kidneys) 2) accumulation of waste products and mucopolysaccharides in extracellular spaces (acting as a barrier), 3) lazy lymphatic drainage, 4) fewer cellular receptors for T4 and T3 5) slower conversion of T4 to T3, 6) lower intracellular demand for thyroid hormones Hypothyroidism, High Antigen Levels, And Lyme John Q: I was in great health, ran more than 20 miles weekly while playing and refereeing soccer. I went to seven doctors and three shrinks before I went to a doctor that understands the relationships between allergies and thyroid. My thyroid was in a low normal range T4=.93 normal range = .9 to 2.0. The problem with my blood was that my antigens were all extremely elevated, thus blocking the low normal T4 from working at the cellular level. IgA, IgG and IgM antigens should all be less than 75—mine were: IgA=540, IgG=177 and IgM=110. You can have your doctor culture your blood and see what your antigens are. When they are out of balance as bad as this, then your thyroid will not work properly and you won’t have an ounce of energy. Note: John Q was subsequently diagnosed with Lyme. After an intensive course of antibiotics, he is doing much better. Although it was his Lyme that led to his high antigen levels, other conditions can lead to high antigen levels, and theoretically, these can interfere with your thyroid use. Hypothyroidism And Hepatitis Paula: I just visited a new doc today. I have hepatitis C liver problems and probably ongoing intestinal problems including candida. I also have a thyroid nodule that was irradiated 2 years ago. I am supposed to have normal TSH and T4. My new doctor has requested several thyroid tests, such as T3 and reverse-T3 that my endocrinologist never did. The new doc is guessing that my dysfunctional liver is not converting T4 to T3, causing hypothyroid symptoms in spite of a diagnosis by an endocrinologist of hyperthyroidism. He also thinks I have possible estrogen dominance since the liver clears excess from blood and mine isn’t doing a good job of that either. (PMS worsening as I approach mid life). Hope this helps someone and proves that we need to find a doc who can see these things that regular docs just don’t see at your run of the mill medical clinics...! Polly: That is interesting that you were almost diagnosed as hyperthyroid instead of hypothyroid. I’ve heard of people being misdiagnosed hyper instead of hypo because they had an inability to convert T4 into T3. These people have some indications of hyperthyroidism, like nervousness and suppressed TSH, and yet they are actually hypothyroid. Glad you found a doctor that is exceptional. Note: See the chapter on Liver Health in Book 1, for some common treatments of hepatitis. The chapter on Estrogen And Progesterone has some suggestions on how to deal with estrogen dominance. Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 24 Armour, T3, and T4 Patti: Just to share my experience here. I switched to Armour after I began to suspect my Synthroid wasn’t working well any more. The dose went up a bit too. But nothing much seemed to occur. My TSH number was low-normal which means good and healthy according to standard medical practice. But I wasn’t feeling better; and I suspected the thyroid still. An additional increase in the Armour led to a horrible migraine that lasted 2 weeks! Eeeeks! Finally still suspecting a thyroid imbalance I switched to taking T4 plus T3 separately. I also avoided getting possibly allergic to the Armour, which had also been a concern. I have actually been much happier with my new thyroid; energy is coming back to normal levels. Apparently some people do better on this regime. My doctor says people don’t know how much T3 is in an Armour dose and this way I can be exact. For what it is worth, it worked for me. I am way more energetic...and just like, NORMAL- A success- Yay! Sarah: I was taking just thyroxine (equivalent to Synthroid or T4) for my thyroid disease. When I first got ill, I thought it was all about my thyroid. So I tried Armour. Armour gave me bad chest pains, but otherwise I did feel better. Now I am back to taking thyroxine (T4), but have added T3 with it in small doses. This, with the anti-candida diet, made quite a big difference in my health. The diet helps with brain fog and fatigue and the T3 seems to help with pollution in London and environmental allergies in general. I think that when the candida is cleared up, I will probably not have to take T3. I could be wrong, but it seems that when your immune system is down and you have dysbiosis, the body has problems converting T4 into T3. Patti: Yes, somehow I stopped converting T4 into T3 as easily as before....interesting, huh? I wonder if this is a common occurrence. I asked my doctor friend why I might have lost my ability to convert to T3 from T4 and he said maybe it’s genetic and was a latent inability that showed up more so as I grew older.... I don’t know why I stopped making the T4 to T3 conversion. I was hoping someone else did. Polly: I have the same problem converting T4 to T3. I think part of my problem is the kidney I had removed. The kidney secretes an enzyme the helps convert T4 to T3. There are several things that are a factor here. Natural progesterone helps you convert T4 into T3. You need certain basic nutrients for this conversion, like selenium, zinc, copper and iron. Low cortisol or not enough glucose or calories in your diet can cause a problem with the conversion too. Cirrhosis of the liver can interfere with the conversion. (About 70% of the conversion of T4 to T3 is done in the liver.) Low body temperature can interfere. There may be some toxin similar to estrogen, possibly from the gut, which is interfering with the liver’s ability to convert T4 into T3. Patti: Thanks for your hypotheses. I bet it’s the one with the estrogen like toxin. Estrogen and I don’t get along at all, and I do take a lot of progesterone. Polly: Patti, how much T4 and T3 are you taking? Patti: 0.1 mg Levoxyl and 12.5 mcg Cytomel Polly: The ratio that you are presently taking is 8 parts T4 to one part T3. That ratio seems a little high on T4 compared to what is in natural thyroid. Natural thyroid is 3 parts T4 to one part T3. Yet, I guess one can’t expect too much of a Thyroid 25 comparison between what you are taking and natural thyroid. Natural thyroid contains more than just T4 and T3. Personally, I was on a grain and a half of just desiccated thyroid for about four years. I had tried increasing the dose to 2 grains and noticed no improvement. Then, we dropped the desiccated thyroid dose from a grain and a half to just one grain and concurrently added 15 mcg of Cytomel (T3). I definitely feel much more energetic and clear-headed with this. I think everyone, especially women, should look into this. Raymond Peat has found that a woman is more likely to need additional T3 than a man. Also, the wrong balance between T4 and T3 in a supplement can actually interfere with the body’s ability to create T3. For me, it doesn’t seem to make much difference if I space the T3 out during the day or just take it all with my morning desiccated thyroid. That is strange because for most people, the T3 needs to be spread out through the day. For the budget conscious, it may be cost effective to fill your Cytomel prescription at a Canadian or Mexian pharmacy. It is very cheap there, possibly even less than the deductible you are paying. In the US, Cytomel is presently very expensive. Geo in Jersey: I definitely do better when I add some Cytomel (T3) to my Armour. I am taking 1 grain (60 mg) Armour + 2.5 mcg Cytomel, both three times daily on an empty stomach. Just the other day, I ran out of Cytomel and tried to simply up the Armour to 1.5 grains and felt really awful. I also remember feeling much better when I initially added the Cytomel. The doctor wanted me to take both only twice a day. This didn’t work for me, so I started taking them three times daily. I was feeling way too unsteady on two times daily. The uninformed doctors pay no regard to the much shorter half-life of T3 with respect to T4. Some doctors recommend taking the T3 six times daily or in the case of Raymond Peat, nibbling on a tablet throughout the day. (I’m not sure how well that would work!) I am fairly sure that I have trouble with converting T4 to T3, probably due to my mercury poisoning. Thyroid and Allergies Patti: I remember when I started Synthroid 12 years ago; my allergies cleared up (to airborne stuff). All of a sudden they had become severe, (actually I never even had allergies before a certain spring and then they exploded to the point of being disabling; I had to wear a dust mask just driving around in the country.) I guess that’s when I needed the thyroid, and the thyroid cleared them up in one month, no more airborne allergies, since then. (I don’t think this applies to mold which is disastrous for me.) Sarah: I find that all the small amount of T3 does for me is to help ward off environmental and chemical pollutants as well as maybe helping with headaches. It doesn’t help with tiredness etc and food allergies. No one has been able to explain why it helps with outside allergens. Polly: Thyroid can raise your blood sugar. Higher blood sugar can reduce your allergies. Often the addition of T3 will improve many different conditions. I almost think that the T3 supplement helps “prime the pump.” It may give your cells just enough energy to help them start making their own active T3 from T4. Sarah, earlier you reported that you weren’t able to tolerate the natural Armour thyroid. (Armour is the most common brand of natural thyroid.) If you have allergies, perhaps you would have been able to tolerate one of the hypoallergenic natural thyroid supplements.

 

Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 26

Avandish: Armour is good but it contains some inactive ingredients that can be allergenic. A company called Bio-tech uses the same pharmaceutical grade thyroid glandular powder that Armour uses, but the only other ingredient in the Bio-tech product is cellulose. Armour contains titanium dioxide (for color), a corn derivative (very allergenic), etc. Bio-tech is also by prescription only and the dosages are the same as used with Armour. Your pharmacist can order it or call Community Pharmacy in Madison Wisconsin if you have trouble finding it. (phone 608 251 3242) I bought it there with a prescription. I didn’t have any problems with the old formulation of Armour, but when I tried the new Armour formulation, I had an allergic reaction (Scratchy throat, trouble breathing, itchy all over). I switched to Bio-tech and the allergy symptoms went away. Polly: The price for the Bio-tech thyroid (called Bio-throid) is presently about the same or sometimes less than the price of Armour. (The price of the Bio-tech product doesn’t ratchet up quickly with dose.) If you want to try it, you can have either your pharmacy or your doctor order it. The Bio-Tech product is encapsulated powder. The Armour is a tablet. If you suspect the Armour isn’t dissolving, you could crush it. Even though I’ve heard of people doing better on Biothroid than Armour, I’ve also heard the opposite. Some people do better on Armour. It is rather hard to figure out what is going on here. Hypothyroidism, Thyroid Nodules, and Progesterone Barbara: I am now on thyroid medication. I have an enlarged thyroid with benign nodules. My blood tests are all normal. The doctor is reluctantly treating me now to shrink my thyroid. Polly: Nodules such as you describe can be formed when the thyroid gland is constantly stimulated beyond its capacity to produce thyroid hormone. If this goes on too long, you get thyroid cancer. As in your case, doctors will usually prescribe thyroid hormone to lower the stimulation of the thyroid gland. This will help reduce the size of the nodules. Raymond Peat, PhD describes something else that can be tried in the situation that you are relating. After the thyroid supplements have reduced the size of the nodules, then you can take natural progesterone to release the thyroid hormone from the colloid. When the thyroid is released from the nodules, this may temporarily create hyperthyroid symptoms of rapid heart rate and higher temperature. This should be a safe protocol, so long as the goiter isn’t too big (about the size of a normal pregnancy goiter), and assuming your heart can tolerate some stimulation. Once the thyroid has been released from the nodules, the nodules will disappear. [7] Since unsaturated oils interfere with the release of thyroid, these are something else to avoid in this situation. Wilson’s Syndrome Michele: Have you checked out Wilson’s Syndrome? There is a web site and an excellent Physicians Manual with very specific testing and treatment protocol that is aimed at restoring T3 conversion. Polly: Yes, I’ve considered Wilson’s Syndrome as a possible problem for myself. I even bought their physician’s manual. Their protocol seems to work best for patients who have suffered a traumatic incident, which lowered their T4 into T3 conversion capability. This protocol gives these patients a much-needed boost to help them start the conversion again. However, I suspect it Thyroid 27 is not the protocol of choice for most of us here. But I could easily be proven wrong. I don’t know until others report on this. Briefly, people with Wilson’s Syndrome are converting too much of their T4 into reverse-T3 instead of regular T3. Reverse-T3 interferes with the action of the thyroid hormone. The treatment for Wilson’s Syndrome is to give the patient so much time-release T3, that it suppresses the patient’s own production of T4. When this happens, supposedly there is no T4 from which to make reverse-T3, and therefore the body stops making the reverse-T3. This protocol will hopefully raise the body temperature and give all the enzymes in the body a chance to recover. After the T3 supplementation has been gradually removed, hopefully, the body has forgotten how to make “reverse-T3,” and only makes normal T3. (The protocol has merit, yet not everything in this theory makes sense. The theory ignores the fact that the body can make reverse-T3 from T3.) Another option that might help is natural progesterone. Natural progesterone inhibits the formation of reverse-T3. Michele: That is a new piece to the reverse-T3 puzzle. I can’t even use the T3 plan because of too many heart irregularities. I got the impression that any severe stress could cause this reverse-T3 to form excessively, like severe candida or mercury toxicity. Polly: If any severe stress can cause this reverse- T3 to form excessively, then even if you temporarily get rid of the reverse-T3 formation, I’d think that the problem would return unless that stressor is no longer present. Therefore, I would guess that the Wilson protocol is more appropriate if the initiating stressor has already been removed. Michele: It is really exciting to me that you said this reverse-T3 process can be inhibited in another direction through natural progesterone. I have been searching for a safe alternative. Do you have any source material for that information that you could direct me to? Polly: Raymond Peat, PhD, mentioned in his book Nutrition for Women (page 20), that progesterone inhibits the formation of reverse- T3. He also stated that reverse-T3 blocks the action of the thyroid hormone. However, that is all the detail he went into on the subject of reverse-T3. It is a relatively small book, but it reads like a set of lecture notes on the interaction between nutrition and hormones. I’ve read it four times, and I still haven’t fully absorbed all the information. Tracy: I’ve been on the T3 for eight months now. When I started taking it in May, I started feeling better right away. I had been trying to get a doctor to treat me for low thyroid for over two years, all of them saying there was nothing wrong because my tests were normal. Then I found the Wilson’s Syndrome website. I got a referral from them and went to see her right away. Finally, a doctor that would listen! I was lucky because she was only 45 minutes from me. Some of the people at their forum have to travel to other states. But it’s worth it. The T3 really is helping; my body is having a hard time holding the temperatures though. Whenever I have stress, mental or physical, my temperatures will drop. I think it is because my adrenals are exhausted from the lack of thyroid function. I have an appointment at an endocrinologist tomorrow to get an adrenal stress index done. I hope I don’t have to argue with him. I think if I get support for my adrenals, the T3 will be able to keep my temperatures up. Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 28 Do Thyroid Supplements Ruin The Thyroid Gland? Polly: Many people are worried that if they take a thyroid supplement, then it might ruin their thyroid gland. This doesn’t happen. Even if you take enough thyroid to completely suppress your own thyroid hormone production, it will not ruin your thyroid gland. If you decide to gradually stop taking it, your body’s own thyroid production will return to its previous level and/or sometimes it will end up even better than before. [8] Do Thyroid Hormone Supplements Cause Bone Loss? Polly: Hyperthyroid people tend to suffer from bone loss. Animal experiments also show that high T4 levels are associated with bone loss. [9] So some caution is warranted with thyroid medication. However, one should not be afraid of taking enough natural thyroid to feel decent. The current medical literature does not show any decrease in bone density associated with correcting a hypothyroid condition. Even giving a large TSH suppressive amount of thyroid doesn’t seem to be much of a problem. [10] In fact, taking thyroid hormone can sometimes improve bone density. A study of using TSH suppressive thyroid to treat depression in 11 patients showed an increase in bone density instead of the expected decrease. [11] Unfortunately, some doctors are too conservative with thyroid supplements. They are so afraid of ruining bones, that they only give enough thyroid to keep the patient’s readings in the low end of normal. This policy does not protect the patient from bone loss. In fact, it may be doing the opposite by harming the patient’s bones. Here are a few mechanisms by which not enough thyroid could lead to bone loss. 1) Thyroid is needed to keep your cortisol levels under control. Cortisol needs to be kept under control because it contributes to bone loss. [12] 2) Low thyroid often leads to hyperprolactinema, which contributes to bone loss. [12] 3) Hypothyroidism produces a predisposition to hyperventillation, and hyperventillation tends to cause calcium loss. [13] 4) Thyroid is needed to keep progesterone levels up. Progesterone promotes the growth of bone. [9] Note: When you first start supplementing natural progesterone, there will be an initial drop in bone density. This is because the oldest, most brittle bone is being discarded in preparation for new bone growth. [14] Excessive thyroid by itself does not cause bone loss. If rats are given adequate calcium and decent nutrition, and if these animals are made extremely hyperthyroid by giving them huge doses of natural thyroid, there was: “… no evidence of failure of calcification in the bones of rapidly growing rats or of decalcification of the bones of older rats” [15] In fact, the bones were about 5% heavier in the severely hyperthyroid rats. (There was more ash in the bones, but most of the extra weight was due to a higher water content. This suggests that the bones were less brittle.) One has to remember that thyroid not only accelerates bone reabsorption, but it can accelerate bone formation. [16] With good nutrition, the body should be able to keep these two processes in Thyroid 29 balance even when there is too much thyroid present. Obviously, good nutrition and good digestion play key roles in keeping the bones strong. Nutrition isn’t the whole picture, but it is key. Vitamin E protects one from bone loss in hyperthyroidism. [17] Other nutrients like calcium, phosphorus, and vitamin K and D are also very important. These nutrients are required to create and maintain strong bones. If you get rid of the intestinal inflammation and dysbiosis, then you will improve the absorption of your minerals and vitamins; this should also support healthy bones. Also gelatin in your diet will likely improve bone density. [18.] The collagen found in gelatin provides a mesh, or net, to attach calcium, phosphorus, and numerous other minerals, resulting in the formation of new bone tissue. In conclusion, adequate thyroid needs to be combined with good nutrition to keep the bones strong. My Pharmacy Doesn’t Carry Natural Thyroids Polly: Not all pharmacists and doctors are familiar with the natural thyroids. There are four brands of natural thyroid: Armour, Westhroid, Naturethroid, and Bio-throid thyroid. Most everyone uses the Armour thyroid. However, once in a while, someone cannot tolerate the Armour. Armour has fillers derived from corn and potato. In the new formulation of Armour (starting in 1996), they also added titanium oxide for coloring. (In one study, 3% of the patients had an immune reaction to titanium dioxide. [19]) Westhroid contains corn, so avoid that if you are sensitive to corn. Bio-throid is hypoallergenic, and only contains the desiccated thyroid and cellulose. Nature-throid is free of common allergens, but it does contain a lot of other binders and ingredients, including PEG. Armour is made by Forest Pharmaceuticals. Westhroid and Naturethroid are made by Western Research. Bio-throid is made by Bio-Tech Pharmacal. Bio-Tech Pharmacal ships the Biothroid thyroid to other countries. At this time, Western Research does not ship outside the US. Forest Pharmaceuticals does not ship Armour to other countries because they do not have the distribution rights outside the US. To purchase Armour outside the US, contact the Broda Barnes Foundation. If you live outside the European Union, a hypoallergenic natural thyroid can be ordered from International Anti-Aging Systems (IAS) without a perscription. Currently they carry 1/4 and 1 grain capsules. (IAS also carries a homeopathic thyroid supplement called Thyrium. So don’t get the two mixed up.) Forest Pharmaceuticals 13600 Shoreline Drive St. Louis, Missouri 63045 phone 800-678-1605 extension 7037 fax 314-493-7457 Western Research 12209 North 32nd street Phoenix, Arizona 85032 phone (623) 879-8535 website www.westernresearchlaboratories.com Bio-Tech Pharmacal 3481 North Hwy 112 Fayetteville, Arkansas 72703 phone 800 - 345-1199 or 501-443-9148 Fax: 1-501-443-5643. website www.bio-tech-pharm.com Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 30 Broda Barnes Foundation PO Box 98 Trumbull, CT 06611 phone 203-261-2101 Fax 203-261-3017 Email for Barnes Foundation: info@BrodaBarnes.org website www.brodabarnes.org. International Anti-Aging Systems (IAS) Channel Islands Great Britain telephone: +44 870 151 4144 website www.antiaging-systems.com.

People on the Internet have surmised that each Nutri-meds pill is roughly equivalent to a fourth grain of the prescription desiccated thyroids. This is not very much, but it is enough to help an adult. One Nutri-meds pill per day is good general nutritional support. If we were still eating blood pudding and other such traditional foods, then we would be getting about a fourth grain in our daily diet. Most healthy people will Thyroid 21 have no problem with this much. However, if you are particularly weak, you need to be more cautious. If you decide to purchase these undenatured thyroid glandulars, then you must take on the responsibility of this choice. Do not abuse them, or the FDA will take away everyone’s right to use them. Especially if this is the first time you have taken such a product, you need some guidance. Look for a progressive MD or seek the advice of a naturopath. You should request that your doctor take periodic blood thyroid tests. Or order your own blood thyroid tests. (See the section on ordering hormone tests in the progesterone/estrogen chapter.) Also, read and understand the precautions section in this chapter. Thyroid glandulars that have not been denatured can be purchased at www.nutrimeds. com/thyroid.htm, phone (888)-265-3353. Both the porcine (pig) and bovine (cattle) glandulars are available. Although people usually react better to the porcine, once in a while, a person will do better on the bovine. The Blood Tests For Thyroid Polly: Many doctors, especially those bound by HMO (Health Maintenance Organization) rules, rely only on the TSH (thyroid stimulating hormone) blood test to screen for thyroid problems. However, this can miss some cases of hypothyroidism. For instance, excess serotonin influence in the brain of people with autism or fibromyalgia could suppress TRH (Thyrotropin Releasing Hormone), which tells the brain to create TSH. Both the autistic and those with fibromyalgia will very often have a lowered TSH response to TRH. [3] These thyroid problems will be missed with just a TSH test. Recently, the conventional dogma has come closer to the position of the alternative doctors. Mary Shoman’s newsletter contains an article entitled “Major Reversal at American Association of Clinical Endocrinologists Regarding TSH and Diagnosing Hypothyroidism.” The essence of the article is that The American Association of Clinical Endocrinologists (AACE) was previously adamant that patients not be treated if their TSH reading were within “normal” limits. Now they state in their material provided for the January 2001 Thyroid Awareness Month that: “Even though a TSH level between 3.0 and 5.0 uU/ml is in the normal range, it should be considered suspect since it may signal a case of evolving thyroid underactivity.” (AACE Press Statement, January 18, 2001) This new lower acceptable TSH range for treating patients is one step in the right direction. At least, if your doctor has heard about it, then it may help. In contrast, many of the alternative doctors had already been using a TSH of 2.0 or higher as the range of readings where they suspect a thyroid problem. Most of the TSH readings from healthy people are around 1.0. Here is a graph of the population’s TSH readings: www.thyroid.org.au/Information/NormalTSH.ht ml Rue: Just wanted to add that candida can cause a thyroiditis that will not raise the TSH above normal limits or just a bit above. However, the person may have symptoms of someone with a TSH of 60. Polly: Yes. If you only test TSH, then you could miss that condition. There are many different tests for thyroid function, and not one of them will catch all the cases of low thyroid. However, some doctors say that all those problems are now solved because they have the latest and greatest tests—free T4 and free T3. Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 22 The hope is that the “free” or unbound thyroid levels will show what the cells actually have available to them for use. Yet, this isn’t completely true. These tests ignore the protein bound thyroid, which is 95% of the thyroid found in the blood. The brain is an example where the protein-bound hormone is the active form, not the free thyroid hormone. But the test for free thyroid is important. If free thyroid is low, yet the bound thyroid looks normal, then this is an indication that the body might be suffering from too much estrogen. When the symptoms of hypothyroidism are present, and yet all the aforementioned blood tests don’t show a problem, then a few doctors will resort to the more expensive Thyrotropin Releasing Hormone (TRH) blood test. This test will show if the brain is having trouble producing enough TSH. The TSH response can be suppressed by stress, lack of sleep, or exposure to lipopolysaccarides from gram-negative intestinal bacteria. [4] About half the people with fibromyalgia will fail this test. About a third of those with autism will fail this test. [5] Many of those with depression will fail this test, especially if it is given in the evening. [6] However, don’t be in a hurry to get the TRH test. With this test, you are given an injection of TRH to stimulate the pituitary into producing TSH. There is a chance that the TRH will overstimulate a weak pituitary and harm it. There would be less risk and certainly less expense if more doctors were willing to give a trial of thyroid based on symptoms. Every doctor should know that the standard blood tests couldn’t possibly cover all the possibilities. Yet many doctors won’t treat unless they have found a blood test that indicates a problem. Even if the blood test shows a problem, they are very reluctant to treat if it is a child. Doctors are acutely aware of peer pressure, their employer’s guidelines, and/or the opinion of their local medical board; they feel their hands are tied. These policies may save the doctors from getting sued, but it isn’t helping the patient. It would be almost impossible to prove that a lack of thyroid hormone treatment was the reason a patient later developed pneumonia, heart disease or cancer. Yet it would be fairly easy to drag a doctor into court claiming that unnecessary treatment harmed someone. Unfortunately, our litigious society creates a situation where it is safer for doctors not to help their patients. Why Isn’t The Blood Thyroid Level A Reliable Indicator? Polly: Many of us seem to require more thyroid hormone than the blood tests indicate. Some think it is due to the yeast or bacteria toxins that are in the gut. Others, point to the interference caused by high antibody levels that can be associated with yeast overgrowth. The blood tests can be dangerously misleading. An example was a man admitted to a French hospital with severe hypothyroidism. He was so bad off that he was exhibiting fullblown myxedema (puffy skin that doesn’t indent when pressed due to accumulation of mucopolysaccharides). Still his blood thyroid tests were normal. (One of the Barnes Tapes by Dr. Hertoghe mentions this incident.). According to a 1994 lecture by Jacques Hertoghe, MD, the blood tests are a poor indicator of the less severe forms of hypothyroidism because there is a slow clearance from the blood of the thyroid hormones when there is hypothyroidism. The thyroid hormones aren’t being used very quickly, so more remains in the blood. This makes it look like there is enough thyroid hormones in the blood even though the patient is hypothyroid. Dr. Hertoghe listed these reasons for the slow clearance: Thyroid 23 1) a reduced blood volume, with overall arterial vasal constriction (including in the kidneys) 2) accumulation of waste products and mucopolysaccharides in extracellular spaces (acting as a barrier), 3) lazy lymphatic drainage, 4) fewer cellular receptors for T4 and T3 5) slower conversion of T4 to T3, 6) lower intracellular demand for thyroid hormones Hypothyroidism, High Antigen Levels, And Lyme John Q: I was in great health, ran more than 20 miles weekly while playing and refereeing soccer. I went to seven doctors and three shrinks before I went to a doctor that understands the relationships between allergies and thyroid. My thyroid was in a low normal range T4=.93 normal range = .9 to 2.0. The problem with my blood was that my antigens were all extremely elevated, thus blocking the low normal T4 from working at the cellular level. IgA, IgG and IgM antigens should all be less than 75—mine were: IgA=540, IgG=177 and IgM=110. You can have your doctor culture your blood and see what your antigens are. When they are out of balance as bad as this, then your thyroid will not work properly and you won’t have an ounce of energy. Note: John Q was subsequently diagnosed with Lyme. After an intensive course of antibiotics, he is doing much better. Although it was his Lyme that led to his high antigen levels, other conditions can lead to high antigen levels, and theoretically, these can interfere with your thyroid use. Hypothyroidism And Hepatitis Paula: I just visited a new doc today. I have hepatitis C liver problems and probably ongoing intestinal problems including candida. I also have a thyroid nodule that was irradiated 2 years ago. I am supposed to have normal TSH and T4. My new doctor has requested several thyroid tests, such as T3 and reverse-T3 that my endocrinologist never did. The new doc is guessing that my dysfunctional liver is not converting T4 to T3, causing hypothyroid symptoms in spite of a diagnosis by an endocrinologist of hyperthyroidism. He also thinks I have possible estrogen dominance since the liver clears excess from blood and mine isn’t doing a good job of that either. (PMS worsening as I approach mid life). Hope this helps someone and proves that we need to find a doc who can see these things that regular docs just don’t see at your run of the mill medical clinics...! Polly: That is interesting that you were almost diagnosed as hyperthyroid instead of hypothyroid. I’ve heard of people being misdiagnosed hyper instead of hypo because they had an inability to convert T4 into T3. These people have some indications of hyperthyroidism, like nervousness and suppressed TSH, and yet they are actually hypothyroid. Glad you found a doctor that is exceptional. Note: See the chapter on Liver Health in Book 1, for some common treatments of hepatitis. The chapter on Estrogen And Progesterone has some suggestions on how to deal with estrogen dominance. Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 24 Armour, T3, and T4 Patti: Just to share my experience here. I switched to Armour after I began to suspect my Synthroid wasn’t working well any more. The dose went up a bit too. But nothing much seemed to occur. My TSH number was low-normal which means good and healthy according to standard medical practice. But I wasn’t feeling better; and I suspected the thyroid still. An additional increase in the Armour led to a horrible migraine that lasted 2 weeks! Eeeeks! Finally still suspecting a thyroid imbalance I switched to taking T4 plus T3 separately. I also avoided getting possibly allergic to the Armour, which had also been a concern. I have actually been much happier with my new thyroid; energy is coming back to normal levels. Apparently some people do better on this regime. My doctor says people don’t know how much T3 is in an Armour dose and this way I can be exact. For what it is worth, it worked for me. I am way more energetic...and just like, NORMAL- A success- Yay! Sarah: I was taking just thyroxine (equivalent to Synthroid or T4) for my thyroid disease. When I first got ill, I thought it was all about my thyroid. So I tried Armour. Armour gave me bad chest pains, but otherwise I did feel better. Now I am back to taking thyroxine (T4), but have added T3 with it in small doses. This, with the anti-candida diet, made quite a big difference in my health. The diet helps with brain fog and fatigue and the T3 seems to help with pollution in London and environmental allergies in general. I think that when the candida is cleared up, I will probably not have to take T3. I could be wrong, but it seems that when your immune system is down and you have dysbiosis, the body has problems converting T4 into T3. Patti: Yes, somehow I stopped converting T4 into T3 as easily as before....interesting, huh? I wonder if this is a common occurrence. I asked my doctor friend why I might have lost my ability to convert to T3 from T4 and he said maybe it’s genetic and was a latent inability that showed up more so as I grew older.... I don’t know why I stopped making the T4 to T3 conversion. I was hoping someone else did. Polly: I have the same problem converting T4 to T3. I think part of my problem is the kidney I had removed. The kidney secretes an enzyme the helps convert T4 to T3. There are several things that are a factor here. Natural progesterone helps you convert T4 into T3. You need certain basic nutrients for this conversion, like selenium, zinc, copper and iron. Low cortisol or not enough glucose or calories in your diet can cause a problem with the conversion too. Cirrhosis of the liver can interfere with the conversion. (About 70% of the conversion of T4 to T3 is done in the liver.) Low body temperature can interfere. There may be some toxin similar to estrogen, possibly from the gut, which is interfering with the liver’s ability to convert T4 into T3. Patti: Thanks for your hypotheses. I bet it’s the one with the estrogen like toxin. Estrogen and I don’t get along at all, and I do take a lot of progesterone. Polly: Patti, how much T4 and T3 are you taking? Patti: 0.1 mg Levoxyl and 12.5 mcg Cytomel Polly: The ratio that you are presently taking is 8 parts T4 to one part T3. That ratio seems a little high on T4 compared to what is in natural thyroid. Natural thyroid is 3 parts T4 to one part T3. Yet, I guess one can’t expect too much of a Thyroid 25 comparison between what you are taking and natural thyroid. Natural thyroid contains more than just T4 and T3. Personally, I was on a grain and a half of just desiccated thyroid for about four years. I had tried increasing the dose to 2 grains and noticed no improvement. Then, we dropped the desiccated thyroid dose from a grain and a half to just one grain and concurrently added 15 mcg of Cytomel (T3). I definitely feel much more energetic and clear-headed with this. I think everyone, especially women, should look into this. Raymond Peat has found that a woman is more likely to need additional T3 than a man. Also, the wrong balance between T4 and T3 in a supplement can actually interfere with the body’s ability to create T3. For me, it doesn’t seem to make much difference if I space the T3 out during the day or just take it all with my morning desiccated thyroid. That is strange because for most people, the T3 needs to be spread out through the day. For the budget conscious, it may be cost effective to fill your Cytomel prescription at a Canadian or Mexian pharmacy. It is very cheap there, possibly even less than the deductible you are paying. In the US, Cytomel is presently very expensive. Geo in Jersey: I definitely do better when I add some Cytomel (T3) to my Armour. I am taking 1 grain (60 mg) Armour + 2.5 mcg Cytomel, both three times daily on an empty stomach. Just the other day, I ran out of Cytomel and tried to simply up the Armour to 1.5 grains and felt really awful. I also remember feeling much better when I initially added the Cytomel. The doctor wanted me to take both only twice a day. This didn’t work for me, so I started taking them three times daily. I was feeling way too unsteady on two times daily. The uninformed doctors pay no regard to the much shorter half-life of T3 with respect to T4. Some doctors recommend taking the T3 six times daily or in the case of Raymond Peat, nibbling on a tablet throughout the day. (I’m not sure how well that would work!) I am fairly sure that I have trouble with converting T4 to T3, probably due to my mercury poisoning. Thyroid and Allergies Patti: I remember when I started Synthroid 12 years ago; my allergies cleared up (to airborne stuff). All of a sudden they had become severe, (actually I never even had allergies before a certain spring and then they exploded to the point of being disabling; I had to wear a dust mask just driving around in the country.) I guess that’s when I needed the thyroid, and the thyroid cleared them up in one month, no more airborne allergies, since then. (I don’t think this applies to mold which is disastrous for me.) Sarah: I find that all the small amount of T3 does for me is to help ward off environmental and chemical pollutants as well as maybe helping with headaches. It doesn’t help with tiredness etc and food allergies. No one has been able to explain why it helps with outside allergens. Polly: Thyroid can raise your blood sugar. Higher blood sugar can reduce your allergies. Often the addition of T3 will improve many different conditions. I almost think that the T3 supplement helps “prime the pump.” It may give your cells just enough energy to help them start making their own active T3 from T4. Sarah, earlier you reported that you weren’t able to tolerate the natural Armour thyroid. (Armour is the most common brand of natural thyroid.) If you have allergies, perhaps you would have been able to tolerate one of the hypoallergenic natural thyroid supplements.

 

Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 26

Avandish: Armour is good but it contains some inactive ingredients that can be allergenic. A company called Bio-tech uses the same pharmaceutical grade thyroid glandular powder that Armour uses, but the only other ingredient in the Bio-tech product is cellulose. Armour contains titanium dioxide (for color), a corn derivative (very allergenic), etc. Bio-tech is also by prescription only and the dosages are the same as used with Armour. Your pharmacist can order it or call Community Pharmacy in Madison Wisconsin if you have trouble finding it. (phone 608 251 3242) I bought it there with a prescription. I didn’t have any problems with the old formulation of Armour, but when I tried the new Armour formulation, I had an allergic reaction (Scratchy throat, trouble breathing, itchy all over). I switched to Bio-tech and the allergy symptoms went away. Polly: The price for the Bio-tech thyroid (called Bio-throid) is presently about the same or sometimes less than the price of Armour. (The price of the Bio-tech product doesn’t ratchet up quickly with dose.) If you want to try it, you can have either your pharmacy or your doctor order it. The Bio-Tech product is encapsulated powder. The Armour is a tablet. If you suspect the Armour isn’t dissolving, you could crush it. Even though I’ve heard of people doing better on Biothroid than Armour, I’ve also heard the opposite. Some people do better on Armour. It is rather hard to figure out what is going on here. Hypothyroidism, Thyroid Nodules, and Progesterone Barbara: I am now on thyroid medication. I have an enlarged thyroid with benign nodules. My blood tests are all normal. The doctor is reluctantly treating me now to shrink my thyroid. Polly: Nodules such as you describe can be formed when the thyroid gland is constantly stimulated beyond its capacity to produce thyroid hormone. If this goes on too long, you get thyroid cancer. As in your case, doctors will usually prescribe thyroid hormone to lower the stimulation of the thyroid gland. This will help reduce the size of the nodules. Raymond Peat, PhD describes something else that can be tried in the situation that you are relating. After the thyroid supplements have reduced the size of the nodules, then you can take natural progesterone to release the thyroid hormone from the colloid. When the thyroid is released from the nodules, this may temporarily create hyperthyroid symptoms of rapid heart rate and higher temperature. This should be a safe protocol, so long as the goiter isn’t too big (about the size of a normal pregnancy goiter), and assuming your heart can tolerate some stimulation. Once the thyroid has been released from the nodules, the nodules will disappear. [7] Since unsaturated oils interfere with the release of thyroid, these are something else to avoid in this situation. Wilson’s Syndrome Michele: Have you checked out Wilson’s Syndrome? There is a web site and an excellent Physicians Manual with very specific testing and treatment protocol that is aimed at restoring T3 conversion. Polly: Yes, I’ve considered Wilson’s Syndrome as a possible problem for myself. I even bought their physician’s manual. Their protocol seems to work best for patients who have suffered a traumatic incident, which lowered their T4 into T3 conversion capability. This protocol gives these patients a much-needed boost to help them start the conversion again. However, I suspect it Thyroid 27 is not the protocol of choice for most of us here. But I could easily be proven wrong. I don’t know until others report on this. Briefly, people with Wilson’s Syndrome are converting too much of their T4 into reverse-T3 instead of regular T3. Reverse-T3 interferes with the action of the thyroid hormone. The treatment for Wilson’s Syndrome is to give the patient so much time-release T3, that it suppresses the patient’s own production of T4. When this happens, supposedly there is no T4 from which to make reverse-T3, and therefore the body stops making the reverse-T3. This protocol will hopefully raise the body temperature and give all the enzymes in the body a chance to recover. After the T3 supplementation has been gradually removed, hopefully, the body has forgotten how to make “reverse-T3,” and only makes normal T3. (The protocol has merit, yet not everything in this theory makes sense. The theory ignores the fact that the body can make reverse-T3 from T3.) Another option that might help is natural progesterone. Natural progesterone inhibits the formation of reverse-T3. Michele: That is a new piece to the reverse-T3 puzzle. I can’t even use the T3 plan because of too many heart irregularities. I got the impression that any severe stress could cause this reverse-T3 to form excessively, like severe candida or mercury toxicity. Polly: If any severe stress can cause this reverse- T3 to form excessively, then even if you temporarily get rid of the reverse-T3 formation, I’d think that the problem would return unless that stressor is no longer present. Therefore, I would guess that the Wilson protocol is more appropriate if the initiating stressor has already been removed. Michele: It is really exciting to me that you said this reverse-T3 process can be inhibited in another direction through natural progesterone. I have been searching for a safe alternative. Do you have any source material for that information that you could direct me to? Polly: Raymond Peat, PhD, mentioned in his book Nutrition for Women (page 20), that progesterone inhibits the formation of reverse- T3. He also stated that reverse-T3 blocks the action of the thyroid hormone. However, that is all the detail he went into on the subject of reverse-T3. It is a relatively small book, but it reads like a set of lecture notes on the interaction between nutrition and hormones. I’ve read it four times, and I still haven’t fully absorbed all the information. Tracy: I’ve been on the T3 for eight months now. When I started taking it in May, I started feeling better right away. I had been trying to get a doctor to treat me for low thyroid for over two years, all of them saying there was nothing wrong because my tests were normal. Then I found the Wilson’s Syndrome website. I got a referral from them and went to see her right away. Finally, a doctor that would listen! I was lucky because she was only 45 minutes from me. Some of the people at their forum have to travel to other states. But it’s worth it. The T3 really is helping; my body is having a hard time holding the temperatures though. Whenever I have stress, mental or physical, my temperatures will drop. I think it is because my adrenals are exhausted from the lack of thyroid function. I have an appointment at an endocrinologist tomorrow to get an adrenal stress index done. I hope I don’t have to argue with him. I think if I get support for my adrenals, the T3 will be able to keep my temperatures up. Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 28 Do Thyroid Supplements Ruin The Thyroid Gland? Polly: Many people are worried that if they take a thyroid supplement, then it might ruin their thyroid gland. This doesn’t happen. Even if you take enough thyroid to completely suppress your own thyroid hormone production, it will not ruin your thyroid gland. If you decide to gradually stop taking it, your body’s own thyroid production will return to its previous level and/or sometimes it will end up even better than before. [8] Do Thyroid Hormone Supplements Cause Bone Loss? Polly: Hyperthyroid people tend to suffer from bone loss. Animal experiments also show that high T4 levels are associated with bone loss. [9] So some caution is warranted with thyroid medication. However, one should not be afraid of taking enough natural thyroid to feel decent. The current medical literature does not show any decrease in bone density associated with correcting a hypothyroid condition. Even giving a large TSH suppressive amount of thyroid doesn’t seem to be much of a problem. [10] In fact, taking thyroid hormone can sometimes improve bone density. A study of using TSH suppressive thyroid to treat depression in 11 patients showed an increase in bone density instead of the expected decrease. [11] Unfortunately, some doctors are too conservative with thyroid supplements. They are so afraid of ruining bones, that they only give enough thyroid to keep the patient’s readings in the low end of normal. This policy does not protect the patient from bone loss. In fact, it may be doing the opposite by harming the patient’s bones. Here are a few mechanisms by which not enough thyroid could lead to bone loss. 1) Thyroid is needed to keep your cortisol levels under control. Cortisol needs to be kept under control because it contributes to bone loss. [12] 2) Low thyroid often leads to hyperprolactinema, which contributes to bone loss. [12] 3) Hypothyroidism produces a predisposition to hyperventillation, and hyperventillation tends to cause calcium loss. [13] 4) Thyroid is needed to keep progesterone levels up. Progesterone promotes the growth of bone. [9] Note: When you first start supplementing natural progesterone, there will be an initial drop in bone density. This is because the oldest, most brittle bone is being discarded in preparation for new bone growth. [14] Excessive thyroid by itself does not cause bone loss. If rats are given adequate calcium and decent nutrition, and if these animals are made extremely hyperthyroid by giving them huge doses of natural thyroid, there was: “… no evidence of failure of calcification in the bones of rapidly growing rats or of decalcification of the bones of older rats” [15] In fact, the bones were about 5% heavier in the severely hyperthyroid rats. (There was more ash in the bones, but most of the extra weight was due to a higher water content. This suggests that the bones were less brittle.) One has to remember that thyroid not only accelerates bone reabsorption, but it can accelerate bone formation. [16] With good nutrition, the body should be able to keep these two processes in Thyroid 29 balance even when there is too much thyroid present. Obviously, good nutrition and good digestion play key roles in keeping the bones strong. Nutrition isn’t the whole picture, but it is key. Vitamin E protects one from bone loss in hyperthyroidism. [17] Other nutrients like calcium, phosphorus, and vitamin K and D are also very important. These nutrients are required to create and maintain strong bones. If you get rid of the intestinal inflammation and dysbiosis, then you will improve the absorption of your minerals and vitamins; this should also support healthy bones. Also gelatin in your diet will likely improve bone density. [18.] The collagen found in gelatin provides a mesh, or net, to attach calcium, phosphorus, and numerous other minerals, resulting in the formation of new bone tissue. In conclusion, adequate thyroid needs to be combined with good nutrition to keep the bones strong. My Pharmacy Doesn’t Carry Natural Thyroids Polly: Not all pharmacists and doctors are familiar with the natural thyroids. There are four brands of natural thyroid: Armour, Westhroid, Naturethroid, and Bio-throid thyroid. Most everyone uses the Armour thyroid. However, once in a while, someone cannot tolerate the Armour. Armour has fillers derived from corn and potato. In the new formulation of Armour (starting in 1996), they also added titanium oxide for coloring. (In one study, 3% of the patients had an immune reaction to titanium dioxide. [19]) Westhroid contains corn, so avoid that if you are sensitive to corn. Bio-throid is hypoallergenic, and only contains the desiccated thyroid and cellulose. Nature-throid is free of common allergens, but it does contain a lot of other binders and ingredients, including PEG. Armour is made by Forest Pharmaceuticals. Westhroid and Naturethroid are made by Western Research. Bio-throid is made by Bio-Tech Pharmacal. Bio-Tech Pharmacal ships the Biothroid thyroid to other countries. At this time, Western Research does not ship outside the US. Forest Pharmaceuticals does not ship Armour to other countries because they do not have the distribution rights outside the US. To purchase Armour outside the US, contact the Broda Barnes Foundation. If you live outside the European Union, a hypoallergenic natural thyroid can be ordered from International Anti-Aging Systems (IAS) without a perscription. Currently they carry 1/4 and 1 grain capsules. (IAS also carries a homeopathic thyroid supplement called Thyrium. So don’t get the two mixed up.) Forest Pharmaceuticals 13600 Shoreline Drive St. Louis, Missouri 63045 phone 800-678-1605 extension 7037 fax 314-493-7457 Western Research 12209 North 32nd street Phoenix, Arizona 85032 phone (623) 879-8535 website www.westernresearchlaboratories.com Bio-Tech Pharmacal 3481 North Hwy 112 Fayetteville, Arkansas 72703 phone 800 - 345-1199 or 501-443-9148 Fax: 1-501-443-5643. website www.bio-tech-pharm.com Hormones, Dysbiosis and Candidiasis The Health Forum—Book 4 30 Broda Barnes Foundation PO Box 98 Trumbull, CT 06611 phone 203-261-2101 Fax 203-261-3017 Email for Barnes Foundation: info@BrodaBarnes.org website www.brodabarnes.org. International Anti-Aging Systems (IAS) Channel Islands Great Britain telephone: +44 870 151 4144 website www.antiaging-systems.com.

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