Lyme Symptoms
My response already fell to page 2.... just to be sure you see it :)* * *
Thanks Paul....
>>Clarithromycin [Biaxin] is a front line drug use against Lyme!
Interesting. Ya, see I took a lot of this in my 20's and suspected even back then that it was tackling more than just my sinuses as i just felt *so much* better with it.
>>..if you read my site you will see that the rise in Lyme mirrors the rise in many so called auto immune conditions ..I believe that is it no coincidence The rise is a a consequence of the altered conditions in the gut brought about by yeast!!!
I had autoimmune activity with a 4+ candida infection.... fortunately it reversed along with it.
>>Thanks for the pat on the back for beating yeast [IBS] its a bit belated ,,I won the battle with yeast back in 2001
Oh, I was just responding to a previous post of yours to me - guess you don't remember :) congrats once again :)))
>>I have been treating very clear symptoms of Lyme since ..The battle is going well ..Too soon to say Im cured but lets say Im enjoying good health at the moment
Glad to hear it..
>>m experimenting with a superior probiotic ..one you will not see on any shelf in a shop Im pleased with initial results .
Interesting. Please do share more if/when you'd like!
>>Salt and Vit C diet for people in our position is a very dicey thing to adopt .We are vulnerable, chronic infection reduces our chances of dealing with many challenges including toxic amounts of salt. To deliberately add a toxic amount of salt to your diet in our position is just plain stupid .
I suppose a revelant q here is 'how much is toxic' ... as dpd has noted, our ancestors ingested a lot
Think it also depends to some degree on the source...
And then you gotta consider that the pharmaceutical alternative is inherently toxic
>>I do think the salt is killing CWD bacteria , I do think they are very vulnerable to many treatments when in the CWD form
Interesting... ya i do actually get a lot of dieoff just from real salt.
>>I also think the seat of infection is in the gut , so the doses with conventional treatments will be just too small , out gut flora is measured by weight ..and any treatment must reflect that ..Dr Cranton uses triple Antifungal therapy to treat yeast ..i can understand why ..Paul
To be honest, Cranton's therapy would have absolutely done me in. If it's any indication of his judgment, this guy actually told me (via someone else) that my severely disabling mcs was a 'good thing.'
Sherry Rogers advocates a much more multi faceted approach. She believes that many things have the ability to alter our gut flora, and in my experience that is true.
Believe it or not, I was able to knock out a 4+ candida infection with a modest amount of diflucan (50 to 100 mg daily), a STRICT sugar/mercury/pesticide/preservative free rotational diet, detoxifying my air and water, antibacterial herbs - particularly uva ursi, nutritient supps, enzymes, probios, enemas, and lots of rest and skilled relaxation.
I do appreciate where you are coming from though. Its hard to conceive of some tiny gun changing over several lbs of gut flora. Its always been a mystery to me as to how I can notice any difference with just one or two probio caps. I have no idea....
>>The dangers salt poses to your health
http://www.wrongdiagnosis.com/news/high_salt_consumption_can_cause_a_range_of_health_problems.htm
Salt Toxicity read the article then take the test
http://www.foodandhealth.com/cpecourses/salt_new.php
Thanks - agreed, something to be careful with!!
Yes , interesting reply , I do remember Shari that you had a cancer scare , what was the outcome of that?Ive puzzled the probiotic thing for years ,were not on our own , a few weeks back I managed to talk with a professor whos field is microbiology , specialising in yeast at that ..A brilliant man but in a world of his own [Why dont the doctors treat yeast if its as common as you say]He posed the same question , why any effect at all with small amounts of probiotic ..i think he was fishing , I didnt have the answer.
You ask what is a toxic dose with salt ..well not much just read the details with the deaths of children killed by salt toxicity .. Administered by their evil mothers.Pace ,Im symptom free at the moment ,no cold hands fog, fatigue anything . I dont think it will last ,going on my history ,symptoms will build & I will be obliged to take abxs again ..but you never know. this is the longest ive gone without abx;s [2 weeks]
I still take Olmestartan [Benicar] at 40mg per day my doc who helps as and when he can prescribes it for mild hypertension
When I found Olmesartan I had mixed feelings ..the drug worked like a dream but I was disappointed to be dependent on yet another drug ..I was doubly pleased when after three months I found the inflammation was mopped up to the extent I could keep inflammation at bay with just 40mg per day [from 120mgper day]. Paul
Thanks Paul, Ya the probio thing is a mystery. All I can guess is that they aren't truly comparable to our own gut flora. Like maybe they are more 'active' or more potent somehow??
Another reason that makes me think this is that my CDSA showed that I was full of lactobacilli yet they seemed to do nothing to halt the candida. But maybe mine are just lazy or stupid :)
Well, the tumor is still there, and I'm still here. I was told that I didn't need a biopsy as it was 'clearly' benign. So I hope. Honestly it still freaks me out some but its extremely rare for these things to be malignant, although mine is quite large. Its a fatty tumor called a 'lipoma.' My dad has a couple (which i didn't even know before) and there is supposedly a hereditary link. Anyway, thanks for asking..
Not sure about the salt. I agree its something to be careful with, but then i've never actually heard of any reports of toxicity with anyone on the protocol. I think the salt c'ers here are also supping with potassium to try to keep the electrolytes in balance.
good talking! shari
Hi Paul,I thought salt was safe up until you started to get huge amounts. I was told the therapeutic amount of 12 grams is far below the toxic amount.
Was there a discussion about this that I missed while I was off the board?
My LLMD just told me to do the Salt/C protocol. He is an MD, integrated medicine, and treats the body as a whole.
I really don't know anymore what to do/think.
Pace
Pace,I am not here to say that salt at the doses we take carry no risks... But I have rarely, if at all, ever seen any discussion of really bad side effects on the LS list about c-salt. I have routinely tested the kidneys and livers and all is fine in that camp, which is good.
But I would stress: TAKE MINERALS and POTASSIUM.... (away from the c-salt).... I have took minerals almost the whole time but not potassium, but now that I do saunas and bikram, I feel it is extra important to do the pottasium.
I think any of these hard core therapies, long term abx, cocktail AF and c-salt, carry some risks. It is naive and helpful to say one is safer than the other when we frankly don't know in the case of c-salt (and do in fact of the potential liver damage for triple abx therapy). We are engaging in a huge experiment here and I think it is important that we be as careful as we can and mitigate the risks as much as we can.
Also if you do net searches for salt, there is conflicting information.... So there you go, just like many things (sun, animal fats, the amount of salt) there are deep divides about the drawbacks and benefits to these things. I am not going to pull a "I absolutely know what is going on" move (which is classically a problem with much of biomedicine) but just admit that there seems to be a lot of people helped with c-salt and so far, horrible reports have not been coming through. The minute there are, I will be sure to broadcast them loud and clear as I am also the first to admit we are operating in a vaccum of sorts.
Go slow, get testing done, and minimize your food salt consumption too if you can....
Anyway, this is not to say that c-salt is totally safe but just to say that many of the alternative therapies we engage in have unknown risks because none of them have been tested in a scientific sense. That said, the risks of leaving lyme untreated is significant too and you have to weigh what treatment makes sense for you.
b
ps--> So you are seeing a new doctor, huh?
think any of these hard core therapies, long term abx, cocktail AF and c-salt, carry some risks. It is naive and helpful to say one is safer than the other when we frankly don't know in the case of c-salt (and do in fact of the potential liver damage for triple abx therapy). We are engaging in a huge experiment here and I think it is important that we be as careful as we can and mitigate the risks as much as we can.That above is inaccurate and misleading Its not naive to say one therapy is safer than another ..
Dr Crantons triple therapy consists of two drugs that remain in the gut and one systemic we know the safety profile of antifungals , its very good the orally taken two gut drugs are know to be safe and have practically no adverse side effects.
While the ****only**** information on ingesting large amounts of salt consists of dire warnings of the ***life threatening***consequences of taking large amounts of salt. Bit of a difference there.
mitigate the risks as much as we can.That above is inaccurate and misleading Its not naive to say one therapy is safer than another ..
*** Dr Crantons triple therapy consists of two drugs that remain in the gut and one systemic we know the safety profile of antifungals , its very good the orally taken two gut drugs are know to be safe and have practically no adverse side effects.So Paul one I imagine is nystatin? Which is the other that remains in the gut (I am interested in the therapy)..
Systemtic AF do carry known risks... And from personal experience, I had a terrrible bout of hepatitis thanks to AF therapy... I was not a very high dose (100 mg of Diflucan) either. My liver enzymes were out the roof and I almost ended up in the hosptial. I was taking it alone too.
*** While the ****only**** information on ingesting large amounts of salt consists of dire warnings of the ***life threatening***consequences of taking large amounts of salt. Bit of a difference there.Life Threatening? With hundres of folks on the c-sal list, there is not once person who has reported needing to go to the hospital for taking the dosage of c-salt they do. So acutely it does not seem life threatning as some systemic AF can be.
I am the first to admit though that there may very well be long term effect of high doses of salt can be a huge problem... Just as can long term effects of abx or systemic AF....
The good thing is it seems like a lot of folks that have been on c-salt for 2 years, make a lot a progress and then go down in their dose to very safe levels (2-3 grams)...
But I guess in the end time will tell.... and for now the jury seems out.
b
Google Dr Cranton yeast for the therapy..Hepatitis, is a viral infection , nothing to do with antifungals ..Its Yeast that makes us susceptible to many co- infections .
To ignore the science and quote from an assumed situation is irresponsible ..Just because a few have escaped adverse reactions doesnt make it safe .
The safety of Antifungals is not in question, the figures quoted in the safety studys are for adverse reactions per ** millions **of doses.
Fact AF are one of the most safest class of drug.
So where do you get the information from to lead you to state life threatening antifungals from? And where do you get the figure of 2 to 3grams as very safe ?
The jury is not out , Facts are facts if you consume large amounts of salt ..you are at considerable risk
Re: Salt Safety, Paul UK, today 14:50Reply To This Message
Google Dr Cranton yeast for the therapy..
*** Hepatitis, is a viral infection , nothing to do with antifungals ..Its Yeast that makes us susceptible to many co- infections .
Actually, doctors, at least in the US, will refer to any liver inflammation as hepatits of the liver and while viruses' are the most common cause, it can be induced by alcohol, meds, and even lyme! (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2912832&dopt=Abstract), which I have had when not taking any sort of drugs or treatment.
General definition:
http://www.netdoctor.co.uk/diseases/facts/hepatitis.htmAlcohol hepatitis:
http://www.cumc.columbia.edu/dept/gi/alcohol.html*** To ignore the science and quote from an assumed situation is irresponsible ..Just because a few have escaped adverse reactions doesnt make it safe .
*** The safety of Antifungals is not in question, the figures quoted in the safety studys are for adverse reactions per ** millions **of doses.
Again again I am not being irresponsible, only pointing out what has been well established, and that is that some systemic AF carry with them risk for liver damage and yes it does depend on which ones. Lamisil is considered to be one of the most dangerous, leading to liver failure and death in 16 peole and some docs think it should be pulled off the market:
http://www.startthehealing.com/warninglist.html
Diflucan and sporonax are much safer... But it is standard practice to have monthly liver exams when on AF drugs... I think this alone shows there are risks...
Believe me as someone who has had 1) liver induced hepatits 2) diflucan induced hepatitis and who has been on various AF for MONTHS (and derived A LOT of help from them), I have done my research on prescription AF. And I hope to wrap up my protocol with another try with AF but again, I am just countering your argument that these are uber-safe.
* So where do you get the information from to lead you to state life threatening antifungals from?
Again Lamisil and Nizoral are the two most dangerous ones but my understanding is that any long term use of systemtic AF should go along with liver testing. This alone does index some level of risk., no?* And where do you get the figure of 2 to 3grams as very safe ?
Well if you do a google search, it seems like most experts agree that 2-3 is totally fine, and even up to 6 grams is acceptable
http://news.bbc.co.uk/1/hi/health/3650578.stm
And if you sweat (because of exercise or sauna), they recommend up to 10, which in my case, I take less than that, even on my c-salt protocol (i do bikram and infrared saunas) yet am deriving a lot from the combo of c-salt...
And you may counter wtih, well aren't we eating a lot of processed foods filled to the gills with sodium? Well the protocol suggests home cooked good, mostly raw veggies, with some fruits.. That is, I would hope most are staying away from processed pre-cooked food that is loaded with the crap.** The jury is not out , Facts are facts if you consume large amounts of salt ..you are at considerable riskFor what? High blood pressure? yes perhaps, but if your pressure is not high, after getting tested, then it seems like you are ok.Kidney malfuntion? Test ok. Liver hepatitis? Seems good so far at leat for me, which after 2 months on AF left me in a lurch..
How about for mineral loss? Very likely, which is what I worry about the most and try to take A LOT of minerals... And I hope it is ok but I don't...
Again I am not saying there are no risks. That is silly. But a lot of these interventions to get rid of these chronic illnesses do carry risk and I would say that monitoring your health and your vital signs is *crucial* which ever protocol you are following. But somehow for you to elevate the saftey of long term cocktail AF seems problematic too.
And if nothing else, we can see that the "science of salt" acutually quite more controversial:http://www.sciencemag.org/cgi/content/full/281/5379/898?ijkey=ATm56Jl8nBVYUAnd I don't see anywhere that ingesting 10 grams can lead to anything life threatning (again I think there *are risks* but again, the jury is out in what capacity).
And I don't see anywhere that ingesting 10 grams can lead to anything life threatning (again I think there *are risks* but again, the jury is out in what capacity).You dont see any information on the life threatening 10grams of salt because no-one is stupid enough to conduct such a study ..i bring you back to the deaths of children poisoned by salt.. check it out google salt toxicity ,Again again I am not being irresponsible, only pointing out what has been well established, and that is that some systemic AF carry with them risk for liver damage and yes it does depend on which ones. Lamisil is considered to be one of the most dangerous, leading to liver failure and death in 16 peole and some docs think it should be pulled off the market:
The FACTS do not support your view ,see below.. and yes we are more susceptible to drug toxicity, metabolising drugs ,metals is a problem for many with a gut dysbiosis.. Testing is important . but lets put the problem in context ..its the pathogens that are the problem and eradicating them is the task .and in that respect .Antifungal drugs are a godsend .The frequency of reported apparent hepatic dysfunctions has varied. An
analysis of 7 key placebo-controlled trials (262 placebo vs 1624 terbinafine
patients) suggested increases of 1.4% vs 3.4% in liver function test
indicators (APase, AST, ALT, g-GT, bilirubin >2x above upper normal). In a
European postmarketing study in 25 884 patients, asymptomatic liver enzyme
increases were reported in 0.17% of patients treated. The reporting
frequency for symptomatic liver disorder possibly related to terbinafine was
1:13 000. The relative risk of acute liver injury in this group was
considered to be 4.2 times the background incidence. In the less controlled
circumstances of spontaneous worldwide reporting, the development of
clinically significant signs and symptoms of hepatobiliary dysfunction for
which no other cause was apparent, and in which terbinafine was considered
the possible causative agent was calculated to be approximately 1:37 000
treated patients. The reporting frequency overall for hepatobiliary events
including elevations in liver enzymes was 1:15 000. Very rare cases of liver
failure, some fatal, have been associated with terbinafine treatment and the
incidence rate is about 1:1 000 000 exposed patients
http://www.rxcarecanada.com/Lamisil.asphttp://www.hc-sc.gc.ca/hpfb-dgpsa/tpd-dpt/lamisil_e.html
http://www.fungalresearchtrust.org/flucon.htmlhttp://www.massgeneral.org/pharmacy/ICU%20Guidelines/fluconazole.htm
-
On the subject of the safety of antifungal meds in particular Fluconazole ,
read the following extract,Its part of The use of fluconazole and
itraconazole in the treatment of Candida albicans infections: a review The
document is very much worth reading. Note the dosage for systemic Candida
infections, up to 400mg per day . Later studies recommend that the dose
start at 400mg The optimal dose quoted is between 400 & 800mg per day .
http://jac.oupjournals.org/cgi/content/full/44/4/429
Fluconazole Saftey
Fluconazole is generally well tolerated over a wide dose range. 7 ,82 ,83
,84 Clinical experience is extensive, with over 16 million patient-days of
treatment with fluconazole since its introduction in the UK, and 300 million
patient-days world-wide. The incidence of side effects is low, and symptoms
are generally mild and do not require discontinuation from therapy.7 The
most common side effects are associated with the gastrointestinal tract
(nausea, abdominal discomfort, vomiting, diarrhoea). Others include headache
and rashes, but these are rarely encountered (incidence of <2%).
Tolerability is high even in special patient groups including children and
severely ill patients with AIDS or cancer.7,85
Although not licensed, high doses of fluconazole (up to 800 mg/day) are well
tolerated in the treatment of immunocompromised patients with severe
systemic mycoses.86,87 Doses of up to 1600 mg fluconazole have been shown to
be well tolerated in studies of AIDS patients with histoplasmosis88 and
cryptococcal meningitis.83,87
In rare cases, particularly in patients with serious underlying diseases
such as AIDS and cancer, abnormalities of hepatic, renal, haematological and
other biochemical function tests have been observed, but the clinical
significance and relationship of these to treatment is uncertain.7 Very
rarely, post-mortem examinations of patients who died with severe underlying
disease and had received multiple-dose fluconazole therapy have revealed
hepatic necrosis: an assessment of the riskbenefit ratio of continued
fluconazole administration for patients in whom a significant rise in liver
enzymes occurs is, therefore, recommended. 89 ,90
Safety profile with children
http://pharmainfo.net/displayarticle10358.html
PaulThanks for the info and indeed, I keep repeating, AF are relatively but not toally safe.
And if 10 grams of salt were life threatning for grown adults, you would seepeople going left and right, all the time, and we don't.So no, not life threatning. Risky for other reasons (yes) not immediately life threatning.
Children should NEVER be put on 10 grams of salt and no one was claiming that.
b
In my opinion, the biggest problem with AF drugs taken for GI tract Candida is that while their efficacy is not in question (they do kill yeasts), for the most part they only bring about temporary relief, since Candida tends to return once therapy is withdrawn. This is true no matter whether we're talking a 2 week Nystatin course or a 6 month triple AF therapy. The only difference (in my experience) is the time it takes for the yeast to re-attain a level that generates symptoms. The above leads to AFs being prescribed repeatedly and long-term, which can seriously damage the liver unless therapy is accompanied by liver enzyme monitoring.
IMO, correct AF treatment should consist of investigation and remediation into the underlying cause for the Candida overgrowth (heavy metals, environmental toxicants, ABX induced dysbiosis, underlying food intolerance, parasitic infection etc), followed by a one off AF therapy, followed by a concentrated course of targeted probiotics to fill the vacuum left by the Candida.
Used this way, AFs are generally well tolerated for short term use.
Since salt therapy has never been tested and there is no mechanism in place to report its side effects, all evidence as to its efficacy and safety is anecdotal. I have noted many people reporting Herxheimer effects lasting months, which logically would indicate one of 2 things:
i. The salt-c therapy is causing symptoms of toxicity, which is what the Herxheimer effect is or
ii. The salt-c kills a sufficient number of organisms to generate symptoms but in no way inhibits its regrowth, thus generating long lasting die-off symptoms
since Candida tends to return once therapy is withdrawnI think that depends on the individual , Dr Crantons success rate for the first pass of treatment of three months is only 30% The % goes up dramatically on the second pass
My treatment took 17 months , I assure you I had ALL the symptoms .
unless therapy is accompanied by liver enzyme monitoring.
Agreed ,absolutely essential, we are already under attack from the toxins generated by yeast & co ,Therapy brings an inevitable increase albeit a temporary increase in toxic load [.herx + drug metabolism]
IMO, correct AF treatment should consist of investigation and remediation into the underlying cause for the Candida overgrowth (heavy metals, environmental toxicants, ABX induced dysbiosis, underlying food intolerance, parasitic infection etc), followed by a one off AF therapy, followed by a concentrated course of targeted probiotics to fill the vacuum left by the Candida.
Research tells us that Chronic fatigue victims have multiple infections, Plus being susceptible to accumulating metals etc; Careful consideration must be given to testing and treating each component of your infection[s]
Its clear that probiotics [proprietary] do not fill the gap .You are victim to the hype with probiotics .they are transient they neither stay or multiply in the gut ..I have all the references you want on that subject.
. The salt-c therapy is causing symptoms of toxicity, which is what the Herxheimer effect is or
ii. The salt-c kills a sufficient number of organisms to generate symptoms but in no way inhibits its regrowth, thus generating long lasting die-off symptoms
I dont think Herx and months of treatment is compatible , Dont forget a herx is a poisoning with toxins released by vast amounts of killed off microbes.. This just would not be sustainable for weeks/months .
I do believe salt kills CWD bacteria , I also believe that there are other drugs available that are less toxic ..My own observations tell me that Nystatin is effective against CWD bac also aspirin ,ibuprofen .I am I touch with one Lyme victim, without a spleen at that who self treated as part of a treatment with ibuprofen and cured herself , and no she didnt burn a hole in her gut ..
since Candida tends to return once therapy is withdrawn
again depends on how long the therapy lasts , if you stop therapy prematurely , then it will come back
. The salt-c therapy is causing symptoms of toxicity, which is what the Herxheimer effect is orii. The salt-c kills a sufficient number of organisms to generate symptoms but in no way inhibits its regrowth, thus generating long lasting die-off symptoms
*** I dont think Herx and months of treatment is compatible , Dont forget a herx is a poisoning with toxins released by vast amounts of killed off microbes.. This just would not be sustainable for weeks/months .
I do believe salt kills CWD bacteria , I also believe that there are other drugs available that are less toxic ..My own observations tell me that Nystatin is effective against CWD bac also aspirin ,ibuprofen .I am I touch with one Lyme victim, without a spleen at that who self treated as part of a treatment with ibuprofen and cured herself , and no she didnt burn a hole in her gut ..Just for the record, I did not have months and months of herx :-) I started c-salt after finishing a dissertation, and then started a postdoc, did a lot of work, found a job, moved to a new place, moved to another place etc... I traveled on average once a month for 9 months while on high doses of c-salt.
I really followed a bi-monthly herx schedule (often around the new and full mooon). I don't think I could trust the method if I felt crappy all the time. And I wonder what is happening with folks who herx for that long. I do think c-salt releases a tremendous amount of toxins, possibly heavy metals and I think that is the "herx" that people describe.
But I can take up to 8 grams of c and salt and lead aa very normal, energitic life. Indeed, I supp with tons of chlorella and minerals and this may make the key difference?? I also take a lot of liver supps, do acupuncture for the liver and do coffee-e... Again whether c-salt or AF or ABX, these are hard on your system and it seems as important for many of us to do these detox protocols.
I am now also chealting 2-3 days a week which has given my mind back... I hope it continues..
So I am intrigued by the ibuprofen. I have heard that aspirin works well on viruses and it does thin blood which can really help as lymies have thick blood.
Paul UK what dosage was she on and for how long? Are there any sties on this?
the b
I really followed a bi-monthly herx schedule (often around the new and full moon)There we go ,full & new moon herxs your herxs are in fact infection flares ,growth spurts its part of the organisms life cycle.
Dr Any Wright in the UK a fellow lyme victim has documented his finding on this ..Simply he finds nothing in the blood when feeling relatively OK, then around the full moon & new moon when symptoms flare, the blood is teeming with organisms ..Thought to be spirochetes .
I dont think it a coincidence when as a spin off of the space program docs looking after the astronauts found nano bacteria grew 5 times faster in zero gravity ..
Its all in my web site . http://www.yeast-candida-infections-uk.co.uk/
The lady in question took up to 2 gram per day For 12 months if I remember It was in addition to antibiotic therapy .. I dont know of any sites that have any extra info ..
Taking Ibuprofen has a duel effect ..reducing inflammation & works as an Antifungal There is good evidence to support AF work against CWD bacteria
Antifungal activity of ibuprofen alone and in combination with fluconazole against Candida species.
Pina-Vaz C, Sansonetty F, Rodrigues AG, Martinez-De-Oliveira J, Fonseca AF, Mardh PA.
Department of Microbiology, Porto School of Medicine, University of Porto, Portugal. micfam@ip.pt
Ibuprofen, a non-steroidal anti-inflammatory drug, exhibited antimicrobial activity against Candida albicans and non-albicans strains. At 10 mg/ml, ibuprofen showed a rapid cidal activity against exponential growth phase C. albicans, accompanied by rapid and extensive leakage of intracellular K+, permeation to propidium iodide, lysis of spheroplasts and severe membrane ultrastructural alterations. These results indicate that the killing of Candida cells is due to direct damage to the cytoplasmic membrane. At 5 mg/ml, ibuprofen inhibited growth; however, it did not kill the yeasts and did not directly affect the cytoplasmic membrane. Evaluation of yeast metabolic vitality with the fluorescent probe FUN-1 showed that growth inhibition induced by the fungistatic drug concentration was due to metabolic alterations. The combination of ibuprofen with fluconazole resulted in synergic activity with eight of the 12 Candida strains studied, including four of the five fluconazole-resistant strains. The MICs of fluconazole for the fluconazole-resistant strains decreased 2-128-fold when the drug was associated with ibuprofen. When in combination with fluconazole, MICs for ibuprofen decreased by up to 64-fold for all the 12 strains studied. These results point to the practicability of using ibuprofen, alone or in combination with azoles, in the treatment of candidosis, particularly when applied topically, taking advantage of the drug's antifungal and anti-inflammatory properties.
PMID: 10966233 see also PMID: 15679664 , PMID: 10952582 , PMID: 11128557 sodium salicylateThis extract is very informative ..the last sentence says it all
The toxicity of salt.
Battarbee HD,
Meneely GR.
The subject of sodium toxicity has been controversial for a long time. There is no question that the element can be noxious when consumed acutely in large quantities and there is little doubt as to cause and effect Conversely the consequences of mederate chronic sodium consumption are much harder to document. The effects are insidious and are subject to modification by a variety of environmental influences such as dietary potassium. In addition most studies of chronic sodium excess have dealt with elusive subject of "essential" hypertension. Interpretations of data have been very difficult, and conflicting reports have occurred. Nevertheless epidemiological, clinical, and animal studies show that chronic excess sodium ingestion acting upon a substrate of genetic susceptibility, is an important etiologic factor in essential hypertension and the expression of its sequelae. Positive correlations have also have been obtained between dietary salt and the incidence of stroke and gastric cancer. Dietary potassium appears to confer some degree of protection from the toxic properties of sodium through some unknown mechanism. Available evidence indicates that a suitable intake of salt for man might be approximately 3.5 g/day and probably less. Salt consumption in most developed countries ranges between 8 to 40 g/day, and modern methods of food processing and preparation deplete the protective potassium. The incidences of hypertension in these countries range between 15 to 40% of their populations, and it exacts a dreadful toll. Recognition of the toxic properties of sodium and knowledge of the mechanisms involved in its toxicity offer great possibilities in the area of preventive medicine It may be possible by the sorting out of hypertension-prone subjects and dietary intervention to prevent or minimize the development of hypertension in susceptible individuals. This says nothing of other aspects of sodium toxicity, of which we are largely ignorant.
PMID: 357085 [PubMed - indexed for MEDLINE]
thanks for the other info paulbut there are herx reactions for lyme... this is well documented and it makes sense that you would also kill lyme when it is flaring. no? b
This is my thought on why some people do experience great benefit from salt therapy. There is a tendency when medical docs fail you to take medical matters into your own hands, and quite often people include modifying their personal diet to try and combat disease. Many so called 'health nuts' tinker with their diet in order to try and cure themselves. Dietary strategies to ward off disease is probably one of the first things people try. I think quite often in avoiding restaurant and processed foods, people tend to end up with a sodium deficient diet - unknowingly. My theory is that the people who greatly benefit from c-salt therapy, are these sodium-deficient people who have weakened their systems by not ingesting adaquete salt levels. When these folk all of a sudden start eating abundant levels of salt, I think it quite likely that they could experience a remarkable improvement in their illness. Unfortunately, it is my opinion that those who have not eaten a sodium deficient diet will not benefit whatsoever from blasting their system with additional salt and in fact could additionaly stress their already taxed bodies. The lesson I have taken from the c-salt crowd is to make sure that I eat enough salt., but beyond that I don't believe taking more salt is going to benefit me one bit. 