Lyme Symptoms

This test is not definitive for Lyme ,but if you predict that your CD 57 count will be low ,,that will gain you credibility

Decreased CD57 lymphocyte subset in patients with chronic Lyme disease.

Stricker RB, Winger EE.

Department of Medicine, California Pacific Medical Center, 450 Sutter Street, Suite 1504, San Francisco, CA 94108, USA. rstricker@usmamed.com

BACKGROUND: Chronic Lyme disease (LD) is a debilitating illness caused by tickborne infection with the spirochete Borrelia burgdorferi. Although immunologic abnormalities appear to play a role in this disease, specific immunologic markers of chronic LD have not been identified. METHODS: We evaluated 73 patients with chronic LD for lymphocyte subset abnormalities using flow cytometry. Of these, 53 patients had predominant musculoskeletal symptoms, while 20 patients had predominant neurologic symptoms. The estimated duration of infection ranged from 3 months to 15 years, and all patients had positive serologic tests for B. burgdorferi. Ten patients with acute LD (infection less than 1 month) and 22 patients with acquired immunodeficiency syndrome (AIDS) served as disease controls. RESULTS: All 31 chronic LD patients who were tested prior to antibiotic treatment had significantly decreased CD57 lymphocyte counts (mean, 30+/-16 cells per microl; normal, 60-360 cells per microl, P<0.001). Nineteen of 37 patients (51%) who were tested after initiating antibiotic therapy had decreased CD57 levels (mean, 66+/-39 cells per microl), and all five patients tested after completing antibiotic treatment had normal CD57 counts (mean, 173+/-98 cells per microl). In contrast, all 10 patients with acute LD and 82% of AIDS patients had normal CD57 levels, and the difference between these groups and the pre-treatment patients with chronic LD was significant (P<0.001). Patients with chronic LD and predominant neurologic symptoms had significantly lower mean CD57 levels than patients with predominant musculoskeletal symptoms (30+/-21 vs. 58+/-37 cells per microl, P=0.002). CD57 levels increased in chronic LD patients whose symptoms improved, while patients with refractory disease had persistently low CD57 counts. CONCLUSIONS: A decrease in the CD57 lymphocyte subset may be an important marker of chronic LD. Changes in the CD57 subset may be useful to monitor the response to therapy in this disease.

PMID: 11222912 [PubMed - indexed for MEDLINE]



Thanks - I'll print that out. .


I actually just received results for my stricker panel yesterday, with great results. My CD57 were at 176, which is nearly double what it was last December at around 90. They were FAR lower 2 years ago, but I don't have those results in front of me. The doc believes I'll start overcoming other infections including candida much better as a result of the increased immunity. I'm hoping for the best.


Yeah ,Good results ,i'll hope with you ...Hows your mineral/metals status , zinc in particular


>> Yeah ,Good results ,i'll hope with you ...Hows your mineral/metals status , zinc in particular

I haven't been tested in the past couple years, but as early as the fall of 1999 it was clear that my minerals were WAY jacked up. Hair analyses showed low potassium, sodium, calcium, and magnesium. I've had a terrible problem with muscle spasms that would improve only with CONSTANT magnesium supplementation. This situation has only improved since commensing lyme treatments in Aug 04.

Pretty much ALL esential minerals were jacked up in the early 00's. My Zn/Cu ratios were the worst, and at the time Mercola put me on zinc picolinate which did indeed normalize my zn, cu, and zn/cu ratio. However, initially the dosage was pretty high and it took at least a year to normalize.

I've taken Zn daily since. For the past few years I've been on 22 mg zinc from picolinate. About 6 months ago I stopped but in a couple weeks I noticed deficiencies in both taste and smell, so I resumed it. For the time being, Klinghardt is muscle testing me dosage, and the 22 mg daily seems the way to go.

I probably should be tested using rbc mineral tests, but frankly Klinghardt doesn't have a lot faith in ANY mineral testing atm. He prefers using his muscle testing, and he's helped me so much that I'm relying on his judgement.

Clearly these bugs wreak havoc on MANY mineral levels, perhaps most importantly in my mind magnesium, but zinc, copper, iodine, selenium, potassium, sodium, calcium, and iron imbalanaces seem to be common problems; Klinghardt certainly believes as much as well.


Muscle twitching is a universal symptom with Lyme its generally considered to be pathogen based! .. Can you recall the initial amount of Zinc picolinate you were taking ..i have read that doses up tp 150mg per day are required ..Did you try the taste test as detailed in the Lancet? Some authorities reckon that once deficient in zinc supplementing is needed for life ..

Im not familiar with Muscle testing , what does that entail?

I agree on the imbalance of minerals & vits ..along with all the other spanners in the works.. Immune responses , amino acid imbalance , metabolising drugs etc;

Im not so sure that hair analysis is useful ..a negative test is not conclusive, it maybe that the process of metabolising metals etc is not working ..In any event the results should be carefully considered Paul

http://www.hriptc.org/zinc_deficiency.html


>> Muscle twitching is a universal symptom with Lyme its generally considered to be pathogen based! ..

Yes, I've seen that the spasms are ubiquitous with lyme. Magnesium clearly manages them for me, but I have to take quite a bit of Mg daily to do the trick. Apparently borrelia (and Klinghardt claims bartonella as well) use magnesium much in the same manner as a lot of bugs use iron.

>> Can you recall the initial amount of Zinc picolinate you were taking ..i have read that doses up tp 150mg per day are required ..

90 mg

>> Did you try the taste test as detailed in the Lancet?

No I haven't. Can you point me to info?

>> Some authorities reckon that once deficient in zinc supplementing is needed for life ..

I hope not! The zinc deficiency often is related to pyrroluria, which many believe is genetic. That would support the notion one would have to supplement for life.

However, Klingardt claims it's so common with lyme that he believes it's likely a symptom of lyme. I'm hoping that's the case.

>> Im not familiar with Muscle testing , what does that entail?

Many folks believe muscle testing is next to worthless, but seeing the relative consistency Klinghardt has with it among various visits, I'm gaining confidence. Muscle represents a family of techniques based on kinesiology.

I found this article on Klinghardt's technique using google, but haven't read it yet...

http://www.nihadc.com/ARTcomplete.pdf>> I agree on the imbalance of minerals & vits ..along with all the other spanners in the works.. Immune responses , amino acid imbalance , metabolising drugs etc;

>> Im not so sure that hair analysis is useful ..a negative test is not conclusive, it maybe that the process of metabolising metals etc is not working ..In any event the results should be carefully considered Paul

Yes, it seems clear that hair analyses are not an exact science... more of an inexact art. However, my initial few hair analyses were way out of wack, complete with massive amounts of uranium and mercury. Certainly intervention was able to normalize a lot of things quite nicely in subsequent hair tests, and I started to feel a lot better at the same time.


Muscle testing , oh dear , I will TRY and keep an open mind ...Couldn't access the actual article in Lancet , this site quotes it and details the test ..I tested negative ...Paul

http://www.advance-health.com/zinc.html#Zinc,%20Testosterone%20and%20Men's%20Health