Plaque Buildup

Has anyone else besides myself noticed during their illness an excessive build up of plaque on the teeth. calcium deposits mainly on the bottom front teeth that can be prised off with something sharp the calcium growing back within a short time? � There is a reason for the question


if you mean on the back of the bottom front teeth, its where your salivary glands under the tonge squirt saliva against the teeth


Yes but it really doesn�t matter where, just the fact that it occurs is enough for me �It�s quite dramatic, your left in no doubt that �something� has triggered the build up ..The articles are spot on . Truss found the link with yeast & bacteria years ago, this info just unravels a few unknowns.

Thing is how to regard this? How to treat.?

There is a chance it's more than a chemical process This catches the eye, nano bac using calcium .So do NB control the process of calcium production as yet another survival strategy?

The researchers had observed, through an electron microscope, nanobacteria particles building shells of calcium phosphate around themselves. They began to investigate whether such particles played a role in causing kidney stones, which are also made of calcium compounds. Sure enough, at the center of several stones was a nanobacteria particle.

In our earlier studies, we have assessed a unique agent, nanobacteria (NB), in kidney stones and hypothesized that NB have an active role in calcium phosphate-carbonate deposition in kidney.

It's clear to me that Antifungals are very effective against NB, especially Lamisil ..Don't know why ..the azoles are effective against spiros supposedly through the p450 pathway & below against TB bacterium� But Lamisil has a different mode of action? However they both work against the cell wall with fungi! so any thoughts?

Fungal link offers TB hope
Drugs used to treat fungal infections might also prove useful against tuberculosis, according to scientists in Britain.
They have found a genetic similarity between the TB bacterium and fungi, which they believe makes the bacterium vulnerable to these drugs. Tuberculosis kills two million people each year, a figure that is rapidly rising in parts of the world where Aids is widespread.
Drugs are available, but they are gradually becoming less effective as the bacterium becomes resistant to them.
So there is an urgent need for new lines of treatment.
Now, researchers at the University of Wales in Aberystwyth say they have found one.
Genome breakthrough
The key was an international research project which sequenced the TB genome - work conducted at the Wellcome Trust's Sanger Centre, Cambridge, UK, and at the Institute Pasteur, Paris, France.
When the Aberystwyth researchers examined the sequence, they discovered that TB contains a gene that is also found in the kinds of fungi which infect humans.
There are already anti-fungal drugs called azoles, which work by blocking this gene.
The researchers tried giving these drugs to a close relative of TB in the laboratory, and found that they killed it.
Price problem
They are now starting experiments with TB itself.
If the drugs do work here, the researchers will have found a completely new way of attacking this tough bacterium.
And as azoles are already widely used, far fewer safety trials will be needed than with new drugs.
The problem area could be price - several of these drugs are still under patent, and according to the World Health Organisation, even those which are not are still priced too highly for the poorest parts of the world.

Terbinafine: mode of action and properties of the squalene epoxidase inhibition.
Ryder NS.
Sandoz Research Institute, Vienna, Austria.

Terbinafine (Lamisil) has primarily fungicidal action against many fungi as a result of its specific mechanism of squalene epoxidase inhibition. Treated fungi accumulate squalene while becoming deficient in ergosterol, an essential component of fungal cell membranes. The cidal action is closely associated with the development of high intracellular squalene concentrations, which are believed to interfere with fungal membrane function and cell wall synthesis. In the case of Candida albicans, growth inhibition with terbinafine appears to result from the ergosterol deficiency. The filamentous form of this fungus is more susceptible than the yeast form. Measurement of ergosterol biosynthesis by incorporation of radiolabelled precursors indicates a correlation between inhibition of growth and ergosterol biosynthesis in a range of pathogenic fungi. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida (Ki = 30 nM). In contrast, inhibition of rat liver squalene epoxidase only occurs at higher drug concentrations (Ki = 77 microM), and is competitive with squalene. Thus, terbinafine has no effect on cholesterol biosynthesis in vivo. Squalene epoxidase is not an enzyme of the cytochrome P-450 type, thereby avoiding potential inhibition of this class of enzymes.

Publication Types:
Review


I have lots of plaque/tartar forming on my bottom teeth. Infact I have ended up investing in my own dental plaque remover (quite cheap from the chemist).


Yes!

I have my teeth cleaned by a hygenist twice a year but really need four times year as it starts building up after three months.


Hi,

I've noticed this exact thing wth plaque build up on the lower front teeth. I asked my dentist about it. According to the dentist it just has to do with an individual's own body chemistry and it was recommended to me that I come in 3x a year instead of 2x per year.

I've noticed that before candida became a problem, I had less plaque build up.

What is the reason for your question?


Well , it seems there�s a direct correlation between nano bacteria & the production of calcium�.Which makes our over production of calcium very understandable �Dysbiosis , altered conditions in the gut promoting the growth of would be pathogenic bacteria ..that is bacteria that is part of natural flora but now unconfined by the symbiotic balance ..Grows and escapes the confines of the gut �The good news it looks like nano bacteria are treatable with Antifungals ..If I�ve got it right Lamisil is very effective � comments?


I have some good news for you.....I cured that. Which of the many things I did to cure it I can`t tell you, but you
are on the right track with dysbiosis causing this phenomena. I can tell you that three months of Lamisil did not do it for me. I believe the problem has to do with low SigA which believe it or notis something that stress reduction seems to help. I think one needs a few months of serious work to make this turn around. I think the whole enchilada from liver cleansing, colon
cleansing and gut repairing need to be
simultaneously worked on.
I do know its possible...my dentist was
surprised...but hey, what did he know.


Im glad you cured it ..I like success stories ...What is siga?

But yes relieve the stress on the IS & a cure is possible , along with the correct treatment with ABX's


Sig A is Secretory Iga.....the immune
system`s defence system for the digestive system.


I've also noticed that dysbiosis affects my eyesight. Have you noticed this?

Dysbiosis must be similar to diabetes in that it affects so many seemingly unrelated parts of the body.


Hi, i've just put some useful past posts together, on Lyme & eyesight plenty of info to consider.

From what Ive read, untreated Lyme in some people progresses and is
divided into stages, just like Syphilis with certain symptoms showing
up in stage III.

In stage III late lyme manifestions are commonly eye problems and
skin problems of a particular type. Trouble is, as Nelly points out,
not too many people are familar with this stage.

Here's an excellent site. Take a look at stage 3 and click on ACA
The picture of the back of the hand is the inflammatory stage of ACA
and the picture of the leg is stage 2 ACA.. when the skin is thinned.

I had 3 areas like the hand pic 2 years ago, the back of my left
hand, (just like the pic in the article) and my left forearm. A few
months ago, I have a large oval on my right forearm, and a fairly
large area on my back (I'm not sure that what's on my back is exactly
the same as my forearm.. but it hasn't responded to any treatment (so
abx are next).

If you suspect Lyme of a long untreated duration,
then it might be ACA if you are infected with b.Afzelii species..
I haven't read that the north america (NA) species manifests this
way.. but who knows.. Lymes probably been around in NA longer than
anyone thinks, and IMO b. burgdorferi could manifest this way also at
stage III.

As you know, a spirochete is only about 250 nanometers wide.
This is why it can't be seen by the human eye, and why it can't be
seen under a microscope unless it's stained. And I guarantee, that
if a spirochete ever did get that far into the eye, the eye would be
so filled up with immune cells that vision would be greatly impaired
(I had my right eye get clogged with immune cells and lost part of the
vision field).

I spent over ten years at the opthalmologist with inflammation in the
eyes (from Lyme). There are definiitely (immune) cells that
caninfiltrate the vitreous (and these CAN be seen as they). They can
clump togeteher, or be attached and look stringy.

I don't think the bugs have any special affinity for the eye, I think
they just go there just like they would any where else. I think most
of the immune cells come from the back of the iris.

Uvetis is very very common in almost all inflammatory diseases.

Docs just control it by a never ending loop of steroid drops, the
steroid drops cause cataract, then the patient get operated on - the
oxidized lens is popped out, and new lens put in, then the whole
thing starts over again.. but the person does *not* go blind..

My eye Doc was featured by National Geographic in the film "Miracle
Docs".. as he and another DOc do cataract operations in field
hosptials set up in the mountains of Nepal/Tibet..They hike in. He
can do a cataract operation in something like 20 minutes..and he's so
cavalier about the operation it just rattles me.Normal pressure in the eye is maintained by normal
drainage thru the angle of the eye. This angle is tiny, and any thing
that changes the proper drainage can increase the pressure..

The normal pressure range is 12 to 20mm Hg.. when it gets up into the
high 20s or into the 30's Doc get really worried and the optic nerve
can be damaged (and blindness result).

Any sustained 'attack' by the immune system causes chronic
inflammation, and this can occurr in the eye, and when it does it's
called Uveitis. (which just means inf;ammation anywhere along the
Uvea tract). A eye Doc can usually pinpoint the cause of the
inflammation by it's 'signature'.. which are the immune cells present
and what damage is where, and what it looks like... and the antigen
(the thing the immune system is after) can be virus, bacteria, yeast
or in the case of autoimmune beleivers- 'self'...

So now you have all these immune cells getting into the humor of the
eyes.. and if they're attached to an immune cell then they're called
immune complexes.. in any case they're all in the eye chamber - and
shouldn't be there.

I had so many cells in my right eye once that they filled up at the
bottom like a snow drift (all waiting to exit thru the angle of the
eye I guess) and I lost part of my top vision field (remember the
brain inverts the image).

I found that if I rigged up a microscope at work in a special way, I
could change the focal point, and reflect the light into my eyes from
a piece of silicon, so that I could see the images within my eyes
better than Opthalmologist could.. as far as cell count within the
eye went.. matter of fact I could see them better.
He wanted to see me every week (at $185.00 a pop) to do a cell count,
but after I proved I could monitor it better the he could - I dropped
the visits to monthly... then to where I'd call him if I saw a big
increase.

In any case.. I tell you all this, because so many people don't think
of the devastating problems that can occur in the eyes in late stage
Lyme. I had Uveitis for over 10 years...

Aggrevation and infiltration of MORE immune cells into my eyes pretty
much was the controlling factor of how I took abx for Lyme..
I could not ignore increased inflammation in the eyes . I was at the
top of the inflammation scale many times with my Opthal. hovering
over me with a 4 inch needle wanting to do steroid injections thru
the eye balls...

I had alot of very troubling vision field distortions during abx
therapy that scared me... a big herx is one thing, but blindness
wasn't too attractive to think about.
You're posts have many many statements that ring true to me.
(I was un treated late stage Lyme - 25 years slow decline - numerous
mis dx

I had hyper sensitivites - and a narrow operating tolerance.

I had alot of neuro (lyme problems) Brain and eye - including
auditory.
some could be almost debiliating - others I looked at almost like
an otherworldly ability..

People just thought I was 'quirky' because I couldn't go shopping in
a big dpt. store (too overwheming) - would close my eyes at the
movies if the camera was jerky movement (I had them closed for about
2 hrs in Lord of the Rings - and not because it was scary). I slowly
lost the abililty so see some shades of colors (and argued in a paint
store 4 times because I didn't think they matched a color I asked
them to mix-) I could get lost on the way home from work- a road I
traveled for years - I could tell who walked past my office (by their
lingering perfume or after shave) I liked 40 watt bulbs instead of 75
watt.. Can't recognize some words - as words (symbols?)
I slowly adapted to living with with these problems - But I
realized I was in a slow spiral downward punctuated with a new dx
about every 5 years (actually thought I'd have an Alzheimers dx in he
next 5 years - and probably would have). Visual disturbances - some
frightening - some pleasant.. I had part of my visual field imparied
for a time- with my Ohpthal worried about the high level of
inflammation in my eyes ( I consistantly refused steroids, even though
I was dx with numerous autoimmune disorders).

One of the biggest most bothersome symptoms to leave me post abx
was 15 years of tinnitis.. high pitched in one ear - fog horned (and
tune changing) in the other. I thought I had a damaged choclea -
turns out it must have been a central brain problem..cuz it started
to change tone - waxed and wanned - then went away!!

When I was FINALLY dx with Lyme I said *no* to an MRI... I didn't
even want to see it. (plus I'd of probably got that MS dx they were
trying to pin on me in 1988).

SO yah- if I ever write a book (and I may) I'll have to have several
sub chapters on neural, visual and auditory disturbances.

I'd really love to sit down with Brian Fallon and talk about
neuro Lyme, compensatory and adaptive changes..

*** PS - do you think it's possible to build some new neural
connections in the brain - adaptive or compensatory - and have them
remain after sucessfull therapy?
I think I am beginning to think that's possible.. and I think I can
tell tell which ones those are -
(I know that sounds nuts - but hey - what the heck - I think it's
possible.. there's alot of the brain we don't normally use)


Good read thanks for printing this. Do you have lyme disease and are you the person that had diabetes?


Yes & Yes ..well i have classic symptoms of a spirochete infection It may be lyme, there are many spirochetes